Toronto home rented by royaltobe Meghan Markle sold for 16 million

first_imgTORONTO – The Toronto home that Meghan Markle rented while dating Prince Harry sold for $1.6 million in January 2018.The Seaton Village property was snatched up by an unidentified buyer for more than its $1.39 million asking price, according to sales data from property website geowarehouse and seen by The Canadian Press.“Suits” star Markle is believed to have lived at the property for at least two years before getting engaged to the prince on Nov. 27 and moving to the U.K.She rented the two-storey house near Bathurst and Dupont Streets from former Flare magazine fashion director Elizabeth Cabral and her husband Kevin O’Neill.The Yarmouth Road home with a deep plum exterior was listed in December and advertised as having three bedrooms, two washrooms, hardwood and marble floors, a fully-finished basement and a two-car garage.At the time, Freeman Real Estate Ltd. said it attracted three registered offers.last_img read more

Freezing Rain warning remains in place for BC expands into Alberta

first_imgFORT ST. JOHN, B.C. – A freezing rain warning remains in place for the B.C. Peace and has been expanded into Alberta.The warning says freezing rain is possible Sunday morning due to a Pacific disturbance crossing the B.C. Peace River region. A few mm of ice accumulation is possible before the system passes through late Sunday morning.An area of freezing rain has moved into west-central Alberta.  Freezing rain will end late Sunday morning.For current road conditions visit www.drivebc.ca and in Alberta, visit 511.alberta.caSee the full warning for both regions below. Freezing rain warnings are issued when rain falling in sub-zero temperatures creates ice build-up and icy surfaces.Please continue to monitor alerts and forecasts issued by Environment Canada. To report severe weather, send an email to BCstorm@canada.ca or tweet reports using #BCStorm.Warnings7:12 AM MST Sunday 13 January 2019Freezing rain warning in effect for:Co. of Grande Prairie near Beaverlodge Hythe and DemmittCo. of Grande Prairie near Grande Prairie and WembleyCo. of Grande Prairie near Sexsmith and La GlaceM.D. of Greenview near DeBoltM.D. of Greenview near Little SmokyM.D. of Greenview near O’Brien Prov. Park and Big Mtn CreekM.D. of Greenview near Sturgeon LakeM.D. of Greenview near Valleyview and New Fish CreekM.D. of Greenview near Wapiti and Shuttler Flats Rec. AreaFreezing rain is expected or occurring.An area of freezing rain has moved into west-central Alberta.Freezing rain will end later this morning.Surfaces such as highways, roads, walkways and parking lots may become icy and slippery. Slow down driving in slippery conditions. Watch for taillights ahead and maintain a safe following distance. Be prepared to adjust your driving with changing road conditions.Please continue to monitor alerts and forecasts issued by Environment Canada. To report severe weather, send an email to ABstorm@canada.ca or tweet reports using #ABStorm. UPDATE #3 – The freezing rain warning has ended in the B.C. North PeaceUPDATE #2 – As of 8:30 a.m. – Grande Prairie RCMP are warning motorists of extremely icy road conditions in Grande Prairie and on Highway 40.  Grande Prairie Rural members are currently responding to a multi-vehicle collision South of Grande Prairie on Highway 40 at the correction line. Travel in the Grande Prairie area is not recommended unless necessary at this time.UPDATE – The freezing rain warning has ended for the B.C. South Peace but remains in place for the North Peace and Alberta Peace.center_img Warnings3:34 AM PST Sunday 13 January 2019Freezing rain warning in effect for:B.C. North Peace RiverB.C. South Peace RiverFreezing rain is expected or occurring.A Pacific disturbance crossing the BC Peace River region has spread freezing rain to the area, as warm, moist air overruns subfreezing air near the surface. A few mm of ice accretion is possible before the system passes through later this morning.Surfaces such as highways, roads, walkways and parking lots may become icy and slippery. Take extra care when walking or driving in affected areas.last_img read more

Finding cures for major illnesses at risk due to biodiversity loss UN

“Sustaining Life” – the work of over 100 experts supported by UNEP, the Convention on Biological Diversity (CBD), the UN Development Programme (UNDP) and the International Union for Conservation of Nature (IUCN) – is the most far-reaching book on this subject to date.The volume’s authors warn that threats to land and marine-based life forms, reduce the chances of creating such medical treatments as safer painkillers, treatments for blindness and re-growing tissue and organs.For example, studies of the southern gastric brooding frog, or Rheobatrachus, showed that baby frogs produced substances slowing acid and enzyme secretions, thus leading researchers to believe that new inroads could be made on treating human peptic ulcers, which affect 25 million people in the United States alone.“But the studies could not be continued because both species of Rheobatrachus became extinct, and the valuable medical secrets they held are now gone forever,” said Eric Chivian and Aaron Bernstein, the book’s key authors.Experts stressed that the conclusions of “Sustaining Life” are not intended to sanction the harvesting of wildlife in a manner which further endangers species, but instead that they should trigger stepped up conservation and management efforts.“Habitat loss, destruction and degradation of ecosystems, pollution, over-exploitation and climate change are among the powerful and persistent impacts that are running down the planet’s nature-based capital, including the medical treasure trove of the world’s biodiversity,” said Achim Steiner, UNEP Executive Director.The head of UNDP, Kemal Dervis, said that people around the world, especially the rural poor, depend heavily on biodiversity, but its loss will “seriously jeopardize our prospects for achieving the Millennium Development Goals [MDGs] by 2015,” he said, referring to the eight poverty targets. 23 April 2008Finding treatments for cancer, thinning bone disease and kidney failure are at risk due to biodiversity loss, a ground-breaking new United Nations Environment Programme (UNEP) book cautioned. read more

Is Canadas middle class shrinking — or does it just feel that

Like a growing number of Canadians, the 65-year-old from Hamilton says he has fallen behind — and that’s a challenge, experts say, to Prime Minister Justin Trudeau’s approach to fiscal policy.A recent poll conducted by Ekos Research for The Canadian Press suggests fewer than half of all Canadians now identify as members of the middle class — a steep drop from nearly 70 per cent in 2002.In Galvin’s hometown of Hamilton, 22 per cent said they’ve fallen behind in their social class in the last five years. That was the highest concentration in the country, tied with Halifax and Kitchener.Another 55 per cent of Hamilton respondents said their situations haven’t improved over the last five years.Ekos president Frank Graves said the numbers point to a large shift in what it means to be a member of the middle class in Canada.Canadians can’t stop using their homes as piggy banks with line of credit debt jumping to record $230 billionOne in three Canadians say they are unable to cover monthly bills as rate hike loomsCanadians are the most indebted people in the world, OECD says“The whole notion of a middle-class dream — ‘I work hard, build a better mousetrap, do better than my parents, my kids do better than me, I get a house, a car, retire in comfort’ — that has all been shattered,” said Graves.Graves pointed to higher income inequality and slower economic growth as reasons for the shrinking middle class.“A lot of people are stagnating or falling behind and they’re not happy,” he said.The telephone poll of 7,882 Canadians was conducted Nov. 7-Dec. 10, 2017 and had a margin of error of plus or minus 1.1 percentage points, 19 times out of 20.While the Liberals have covered their bases by expanding their appeals to the middle class to include “those working hard to join it,” Canadians like Galvin have no such aspirations.He has two bachelor’s degrees from the University of Guelph and spent most of his career working in his field. However, after he lost his job more than a decade and a half ago, he has struggled to make ends meet.People feel like they are working harder and not getting ahead Most of that $40 billion, split between federal and provincial investments, won’t start rolling into communities until after 2020. Mayo said communities need more of that funding now to address a growing housing crisis and the mayors of Canada’s biggest cities agree.Last Thursday, the Federation of Canadian Municipalities big-city mayors caucus met Finance Minister Bill Morneau to ask him to speed up the flow of cash.Edmonton mayor Don Iveson said the money is needed faster so that cities can focus on repairing hundreds of thousands of affordable housing units as soon as possible.“There are units that are not … habitable right now because they’ve been waiting so long for that investment and we’d like to get those back in the hands of Canadians who need them and create the jobs now, not in a year or two,” Iveson told a news conference Thursday.Housing isn’t an issue for Galvin but, as far as he’s concerned, more help for low-income Canadians can’t come soon enough.“All you have to do is walk around downtown Hamilton to see what the effects of poverty and low-income work are.” “I was unable to get meaningful middle-class work again and ended up doing a lot of contract and short-term work,” said Galvin.The loss of his wife, Norma, in 2002 and a worsening gambling addiction only made things worse.“I don’t really see myself as a middle-class person,” said Galvin. “I’ve had many years of precarious employment and it’s been a long time since I actually had a professional, middle-class type of job.”Despite now having full-time work as a security guard and receiving Canada Pension Plan benefits and Old Age Security, Galvin still worries about the future.Many in his community and across the country share that uncertainty, according to Sara Mayo, a social planner at Hamilton’s Social Planning and Research Council.“People feel like they are working harder and not getting ahead,” she said. “That is seen across Canada and certainly in Hamilton as well.”One possible solution to the growing problem, said Mayo, is for the federal government to speed up its funding for the National Housing Strategy, a 10-year, $40-billion initiative to provide more affordable housing to lower-income families.All you have to do is walk around downtown Hamilton to see what the effects of poverty and low-income work are OTTAWA — Computer programmer David Galvin should be the quintessential beneficiary of next week’s federal budget, which is expected to continue the Liberals’ persistent rhetoric and focus on bolstering the middle class.He is educated, has had a career in advanced technology and lives in the economic heartland of southern Ontario.But Galvin no longer includes himself in the middle class.The whole notion of a middle-class dream — that has all been shattered read more

Court papers proof political pressure rushed pipeline approval First Nation

Court papers proof political pressure rushed pipeline approval: First Nation by Bob Weber, The Canadian Press Posted Sep 28, 2016 1:22 pm MDT Last Updated Sep 29, 2016 at 7:40 am MDT AddThis Sharing ButtonsShare to TwitterTwitterShare to FacebookFacebookShare to RedditRedditShare to 電子郵件Email EDMONTON – An Alberta First Nation says court documents suggest political and industry pressure hustled approvals for an oilsands pipeline through regulators and reduced aboriginal consultation.“Our concern is that this project was being pushed through too quickly and it would not meet the standards for consultation and review,” said Eriel Deranger of the Athabasca Chipewyan First Nation. “That’s exactly what happened.”Officials with the Alberta Energy Regulator say repeated communications from political staff were attempts to understand a new approach to aboriginal consultation, not an attempt to hurry it along.Earlier this month, the band filed a request with the Alberta Court of Appeal for a judicial review of consultations done ahead of approvals issued to TransCanada Corp. (TSX:TRP) for the Grand Rapids pipeline — a 900,000-barrel-a-day line from the oilsands to Hardisty, Alta. The band says it wasn’t given enough input.Court filings from the Alberta Energy Regulator have emerged that appear to back the band’s allegation.TransCanada applied for approvals in November 2013 and by March the following year had submitted records to the province’s Aboriginal Consultation Office. The office assesses how much input is due First Nations and whether that requirement has been met.The office had recently been created by the governing Progressive Conservatives and Grand Rapids was its first major file.By April 2, an official from the Alberta Energy Regulator wrote the consultation office and said: “We’ve been directed to move the Grand Rapids pipeline project to a hearing ASAP.”TransCanada was already unhappy.An April 8 email from the consultation office’s director to the assistant deputy minister of Aboriginal Affairs said TransCanada officials had expressed concerns at a recent meeting.“I think the frustration of the developing process is affecting some of these concerns,” it read. “TransCanada’s treatment of our staff … has been minimally professional and on the border of bullying.”Another April 8 email from a different office staffer said TransCanada was repeatedly calling and meeting with the consultation office.On April 14, an official with the regulator wrote: “The review and decision for the Grand Rapid pipeline project is being accelerated to attempt to allow construction in September 2014.“The Grand Rapids pipeline project is of particular interest to ministers and senior officials from the (provincial government and the regulator).”A day later, Grand Rapids had been bumped to the head of the line as a “priority file.”“This will not be the routine way of doing things going forward,” said an email from the operations director. “This is an exception due to the higher level of interest in this project.”Another office manager expressed similar concerns.“I share your concern about the ‘urgent’ review of this file … but I think we will have to be flexible on this one given the level of political interest.”The office was worried the regulator was too focused on meeting TransCanada’s request for a June hearing date.“My concern is that AER does not speak for us in terms of timelines,” said an email from the office director on April 16.Shortly after, TransCanada officials met with the deputy minister of Aboriginal Affairs.By May 8, the consultation office had filed what it called “a letter of adequacy to date” that acknowledged “the process is still evolving.”The office ultimately ruled the First Nation wasn’t entitled to full consultation on Grand Rapids, even though the pipeline would cross the band’s traditional territory.A hearing was held in June and July of 2014. The Athabasca Chipewyan were granted standing, but pulled out over concerns they weren’t given funding or time to consider proposal changes.TransCanada says it provided the band with some funding, partly intended to help them review the project. At the time, Chief Allan Adam said TransCanada showed little interest in the band’s concerns and was more concerned with how much it would cost to “buy us off.”The pipeline was approved in October 2014 and construction has begun. It is to go into service next year.Bob Curran, a spokesman with the Alberta Energy Regulator, said in an email to The Canadian Press that proponents often request expedited hearings.“It is not unusual for project proponents and hearing participants to request specific timelines of the AER, to accommodate for things like construction schedules, farm harvest, etc. regardless of the size and type of project,” he wrote.“The AER responds to all stakeholders, whether government, industry, or landowners, in the same manner with the same information.”Government and industry were trying to understand a new process, said another regulatory spokeswoman.“There were questions seeking clarity from stakeholders,” said Carrie Rosa in an email. “The AER responded to all stakeholders, whether government, industry, or landowners, in the same manner with the same information.”TransCanada spokesman Mark Cooper said the company was trying to get a sense of the regulatory timeline so that it could keep its commercial commitments.“At no time did we suggest anything but a proper review of the Grand Rapids project and our indigenous engagement efforts.”TransCanada first met with the Athabasca Chipewyan in 2012 and made “made considerable efforts to engage” with the First Nation, Cooper said in an email. The band was given the same chances for “engagement” as other area First Nations, he said.Alberta’s NDP government declined a request for comment. It has begun reforming the Aboriginal Consultation Office, but it remains largely intact.The band’s request for a judicial review is to be heard in a Calgary court Nov. 8.— Follow Bob Weber on Twitter at @row1960 read more

At Least Phil Jackson Didnt Leave The Knicks In Ruins

The rookies were a different story. Jackson famously preferred Jahlil Okafor to Porzingis, but should be credited for taking a talented but risky prospect. The same goes for trading second-round pick swaps for Willy Hernangomez, a viable center of the future, provided we live long enough to see a future without Joakim Noah on the books, and signing Mindaugas Kuzminskas. And last week’s draft selection, 18-year-old Frank Ntilikina, is a risky, home-run type pick at a draft position in which Jackson could have taken safer players with lower ceilings.Using the same CARMELO method as we did for the veterans, the key Knicks rookies look far better. They project to produce $203 million by 2020, but will have been paid just shy of $43 million. Naturally, that surplus is made possible by the nature of the rookie scale, which artificially depresses pay for young players, but even going only by the real and projected value, this group of young players has been and will be worth far more than the veterans Jackson acquired. And the value isn’t all tied up in Porzingis, either — Hernangomez and Ntilikina both project to produce at a high level.With Jackson on the way out, the expectation is that coach Jeff Hornacek will have the freedom to move away from Jackson’s much derided triangle offense. Dolan is teasing the idea of chasing former Denver Nuggets executive Masai Ujiri, who helped pants New York in the ill-advised trade for Anthony, and then again in the even more lopsided Andrea Bargnani deal a few seasons later when Ujiri was working for the Toronto Raptors. (Somewhat infamously, Ujiri nearly traded Toronto’s star point guard Kyle Lowry to New York before Dolan, hesitant to be humiliated by Ujiri once again, called off the trade at the 11th hour.)The Knicks, who were 80-166 under Jackson, 29.5 games under their preseason Vegas win totals, are in possession of all of their future first-round draft picks for the first time in a decade.2Hell, the last time the Knicks’ draft outlook was promising for consecutive years was 2005 and 2006, when they had back-to-back seasons with multiple first-rounders. In 2005 they drafted Channing Frye and David Lee, and traded Kurt Thomas for Quentin Richardson and the draft rights to Nate Robinson. The following season, the team drafted Renaldo Balkman and Mardy Collins. Things are looking up.And so the Knicks move on to the next stage of their development, better off than they were three seasons ago. Phil Jackson did a good job — except for the parts where he didn’t. Or perhaps he did a world-historically bad job, except for a few draft picks that went his way. It was a mixed bag, full of drama and triangles, and maybe the best thing to be said about Jackson’s Knicks is that they never managed to completely bungle the future. But in this town, that’s not nothing. It’s borderline groundbreaking. Stick around long enough and even the New York Knicks might have a bright future to sell you.VIDEO: Phil Jackson’s legacy with the Knicks isn’t all bad In just three full seasons, Phil Jackson inflicted as much psychic distress on the New York Knicks fanbase as any executive in New York’s recent, storied, terrible history. Jackson signed with the Knicks on March 18, 2014. News broke on Wednesday morning that he’s leaving.Yet the fans’ discomfort was only possible, in large part, because Jackson’s front office drafted well and unearthed talented young players. Jackson built the team of the future, and then set about imperiling it.Jackson’s exit ends several weeks of turmoil which saw him feud openly with Carmelo Anthony over his no-trade clause (which Jackson himself negotiated) and entertain trade possibilities for Kristaps Porzingis, either in earnest or to send the young star a message to fall in line. It was a messy end, but then, things have been a mess for a while now.In Jackson’s first offseason, he made the biggest decision of his tenure: re-signing Anthony to a 5-year, $124 million contract, which included a no-trade clause. He also traded Tyson Chandler and Raymond Felton for then-33-year-old Jose Calderon, a handful of cap filler and a pair of second round picks. Not quite an earth-moving rebuild, but not terrible.The following season, the Knicks made a three-team deal that sent J.R. Smith and Iman Shumpert to Cleveland (and three straight Finals appearances), but returned three marginal players and a 2019 second-round pick. That offseason, the team drafted Porzingis with the No. 4 overall pick, and signed Robin Lopez to a 4-year, $55 million deal. The roster rounded out with peripheral free agents Arron Afflalo and Derrick Williams and a trade for Kyle O’Quinn. Then the real trouble began.In the summer of 2016, Jackson signed Joakim Noah to a 4-year, $72 million contract, and traded Lopez (and his favorable contract), rookie Jerian Grant and Calderon to the Chicago Bulls for Derrick Rose, Justin Holiday and a second round pick. Rose remained a ghost of his former self; Noah was injured, ineffective and more expensive than Lopez.Going by FiveThirtyEight’s CARMELO projection system,1CARMELO has been updated to once again use Real Plus-Minus, though it’s now blended with Box Plus-Minus. We’ll have more details in a few days, but for now, these numbers won’t match the ones in the interactive. we can see just how badly Jackson overshot on the veterans he acquired. The seven most significant players he brought in or re-signed — Anthony, Rose, Noah, Afflalo, Courtney Lee, Lopez and Calderon — made or will make a combined $253 million from the 2014-15 season to the end of the 2019-20 season from the Knicks. Over that same time, they will have produced $134 million of value. The Knicks overpaid by half. read more

The 9 at 9 Wednesday

first_img Wednesday 20 Feb 2019, 8:46 AM Tweet thisShare on FacebookEmail this article The 9 at 9: Wednesday Here’s the news as you start your day. Feb 20th 2019, 7:47 AM 11,488 Views Share2 Tweet Email Image: Shutterstock/StudioByTheSea https://jrnl.ie/4502964 center_img By Hayley Halpin No Comments Get the 9 at 9 News audio Short URL Updated Feb 20th 2019, 8:46 AM EVERY MORNING TheJournal.ie brings you all the news you need to know as you start the day.1. #BLUE LIGHTS: Irish Coast Guard staff and volunteers have been told they are no longer permitted to use blue lights and sirens on vehicles while driving.2. #NO-CONFIDENCE: Minister for Health Simon Harris will today face a no-confidence motion in the Dáil.3. #CHILDREN’S HOSPITAL: The majority of Irish people think the government should re-tender the contract for construction of the National Children’s Hospital. 4. #EUROMILLIONS: The National Lottery is asking the winner of last night’s €175 million EuroMillions jackpot in Ireland to sign the back of the ticket. 5. #RTÉ: RTÉ could enjoy an advertising boost if UK-based channels are blocked from access to the Irish market in the case of a no-deal Brexit.6. #JOBPATH: Only 11,334 people out of 206,000 who have taken part in JobPath sustained employment for over 12 months.7. #HPV: The rapid scale-up of the HPV vaccine could virtually eliminate cervical cancer in a handful of rich countries within three decades, according to researchers.8. #MASS GRAVE: An excavation has begun at a second mother and baby home to determine the real number of remains which lie in its “Angels Plot”, the Irish Daily Mail has reported. 9. #AUDIOLOGY: Almost 60 families in west Ireland have received apologies in recent weeks over failings in audiology services provided to their children, RTÉ has reported. On the go? You can now listen to the 9 at 9 as an audio bulletin from TheJournal.ie, supported by Volkswagen. Get started by hitting the button below. Image: Shutterstock/StudioByTheSealast_img read more

55 Left Without Care After Juneau Daycare Abruptly Closes

first_imgInfant and toddler care facility Spunky Sprouts Too in Juneau shut down abruptly at the close of business Wednesday after key staff members quit. Its preschool, Spunky Sprouts Learning Center, is closing at the end of the month.Listen now:Heather Carlton and 2-year-old son Theo were at home Thursday after Spunky Sprouts Too suddenly shut down. (Photo by Lisa Phu/KTOO)Parents of 55 infants and toddlers have been scrambling to find childcare after Spunky Sprouts Too shut down.Heather Carlton stayed home from work Thursday morning to figure out where her 2-year-old son Theo will now go to daycare.She says she got a call early Wednesday from a Spunky Sprouts employee about the imminent closure.“I was in a state of panic trying to figure out, ‘What am I going to do? How am I going to find somebody to watch him on such short notice?’ You know, there’s already very limited options in Juneau anyways,” Carlton says.Carlton also has a 4-year-old named Arlo who’s been going to Spunky Sprouts for a few years. She says she’s been happy with the care.“He was very quickly potty trained. His reading skills – very satisfied with it. He’s moving along very well so I’m very sad about having to make any sort of change and possibly disrupt his education,” Carlton says.Carlton found spots at another daycare for both kids, but other parents haven’t been as lucky.Spunky Sprouts administrator Shamila Scalf says staff members started quitting in September. She says some worried they wouldn’t be paid. Scalf has worked at the center for three years and says, as long as she’s been there, Spunky Sprouts has always had budget issues.This sign was found on the door of Spunky Sprouts Too located on 9315 Glacier Highway. (Photo by Lisa Phu/KTOO)Administrators say they received instructions by email from owner Adam Hendren to distribute three letters to parents on Sept. 29 about downsizing and a change of facility.Spunky Sprouts Too for infants and toddlers was located off Glacier Highway in the Mendenhall Valley. The preschool, Spunky Sprouts Leaning Center, is in Aldersgate United Methodist Church, also in the valley.One letter says the infant program would end Oct. 31. The other letters say the toddler andpreschool program would move to the Church of the Nazarene.So, according to the letters, three programs in two buildings were supposed to become two programs in one building.Instead, the infant and toddler programs shut down Oct. 1 when the main administrator quit and other staff members followed. And, Scalf says, the preschool center is not moving as indicated in the letter – it’s closing at the end of the month.But due to lack of staff, she’s already turning some children and parents away at the start of each day. Scalf is the only staff member remaining at Spunky Sprouts with a Child Development Associate credential. State regulation says there can be no more than 30 children under her supervision.“I have 37 registered, paying their fee every month, and I have to send home at least seven. Whoever comes in, number 31, I have to say, ‘I’m sorry, I cannot provide care for you because there’s nobody else,’ and it’s embarrassing,” Scalf says.Childcare center Puddle JumpersDevelopmental Learning Center closed in August. After both Spunky Sprouts centers close, only six licensed full-day childcare centers are left in Juneau, according to the Association for the Education of Young Children. There are two part-day childcare centers. Their total capacity is 288 kids.There are 15 licensed in-home childcare providers with capacity for 143 kids.“We have the worst situation in the state for childcare right now,” says Joy Lyon, executive director of the Southeast chapter of AEYC.“The number of parents searching for care is way, way off the charts in Juneau. There was only one space for every five children that needed care and now I think that’s dropped to one space for every six children needing care,” Lyon says.She says her office has been flooded with calls, emails and visits from Spunky Sprouts parents, many in tears.“We do regular updates of all the programs to find out what openings are available and there are very few openings,” she says.Lyon says there’s a group working on starting a childcare program to serve the Spunky Sprouts families, a process that could take anywhere from one to three months.Every first Tuesday of the month, AEYC hosts a networking opportunity for parents struggling to find childcare. The next event is Oct.7.Spunky Sprouts Learning Centers owner Adam Hendren did not return calls for comment. His wife Jennifer started Spunky Sprouts. According to state records, the first business license for childcare in her name dates back to 2007.last_img read more

Micromax Canvas 4 Teased Again New Image Hints at Full HD 1080p

first_imgIn the countdown to the Canvas 4 launch, Micromax has again revealed another teaser image of the smartphone which hinted at a full HD display.The new image posted on the company’s Facebook page showed a girl looking out the window from a train and held a caption that read: “Playing videos can be double the fun than staring at life through windows”.Like earlier images, not much can be established from the picture and the caption accompanying it. But some reports suggest that it could be an indication of a full HD 1080p display or the new screen unlock feature.It was already reported that the next Canvas smartphone may have the new unlock feature, as suggested in previous teaser images posted last week. The images showed the iconic iPhone unlock bar and carried a caption “CAN unlock without touch?” There was also a text that read: ‘Don’t’.Though Micromax is yet to announce the specifications of Canvas 4, the smartphone received a very good response in terms of pre-orders which began on 28 June. The company received more than 4081 pre-orders for Canvas 4 in the first seven hours itself.As the launch date of the Canvas 4 smartphone edges closer, rumours about its specification have gained momentum. Its expected features are a 5.0-inch IPS HD 720p display, 1.2GHz MediaTek MT6589 quad-core processor, Android v4.2.2 out-of-the-box, 13.0-megapaixel rear camera, 5.0-megapixel front-facing camera, 2GB RAM, 8GB of internal memory, 3,000mAh Li Ion battery and connectivity features such as Dual SIM, Wi-Fi, 3G, mini USB 2.0 and Bluetooth. The highly-anticipated smartphone, which will debut on 8 July, is likely to be priced ₹15,990.last_img read more

Visiting the land of watches Switzerland

first_imgHave you ever thought of what you can do, but you do not have to do just for the sake of it? Well if you have, then you might give it a thought of visiting the land of chocolate. Switzerland Tourism launched their Winter Campaign for this year with their new tagline ‘You can… but you don’t have to’, and their Summer Campaign – ‘Nature wants you back’ for the upcoming year recently in the national Capital.With the growing demand in adventure sports among Indian tourists, Switzerland is a hotspot for such adrenalin rush. One can choose from skiing, sledging and snowboarding in the snow covered Alps, while someone who is looking for a rather leisurely vacation, can opt for a relaxed trip soaking in the beauty of the breath-taking scenery and serenity of the country. Christmas markets, open air hot springs and igloo stays are also available during the winder for the visitor looking for pure white relaxation.  Also Read – Add new books to your shelfWith places like Zurich, Basel, Ticino and Matterhorn to visit, and the daily Swissair flights from Delhi and Mumbai, one can experience the blend of three cultures in Swtizerland as the country is surrounded by France, Germany and Italy. The Summer Campaign will be headed by Bollywood star Ranveer Singh as the brand ambassador of Switzerland Tourism.The summer focus for the campaign as well, will be packed with an array of activities like sky-diving, wakeboarding, canyoning combined with Switzerland’s best touristic and nature highlights. Also Read – Over 2 hours screen time daily will make your kids impulsiveClaudio Zemp, Director – India, Switzerland Tourism, said, “In India we see people getting more adventurous these days. They do not only want to take a cable car up a mountain and take pictures but also want that thrill and rush which one gets while doing adventure sports.  With a versatile and energetic personality like Ranveer Singh on board, we would like to showcase that Switzerland is not only about scenic beauty but also has many activities and adventures to offer to the more experiential Indian traveller. Winter is coming up and it is an absolutely beautiful time to visit Switzerland. One can enjoy various winter activities and explore their hidden passion for adventure with sports such as skiing, snow-shoe trekking, tobogganing. Ranveer’s next trip is going to be in winter.” Ritu Sharma, Deputy Director, Switzerland Tourism India, said, “Our new campaign is all about telling people that holidays in Switzerland can be anything that you want – there are lots of options for adventures and activities both in winter and in summer but if you would rather have a more relaxing holiday that’s absolutely possible too. Although Indians love to go on a vacation during the summers, we do hope for a change after this campaign. Apart from the picturesque natural beauty, Switzerland is also a complete package for families and honeymooners who are not only looking at a relaxing vacation but also crave some adventure.”When stepping into a country like Switzerland, it is not just the natural beauty one has to admire, but also the public transport. For the convenience of tourists, they have ‘Swiss travel pass’ which is an all-in-one ticket for all transportations in the country. Travelling around town one might like to visit the FIFA World Football Museum. Basel’s tri-border region at the Rhine harbour marks the meeting point between Switzerland, Germany and France that makes the city unmistakably lively and innovative. Animal lovers can also take a walk with the penguins in the Basel zoo every morning! To witness a little bit of Italy in Switzerland one can head over to Ticino which will be launching the Gotthard base tunnel- the longest tunnel in the world, in December. How many hands up for a winter trip to Switzerland?last_img read more

Answers to 6 Burning Questions From App Entrepreneurs

first_img 6 min read Free Workshop | August 28: Get Better Engagement and Build Trust With Customers Now December 26, 2016 The web ecosystem is far more evolved than the mobile app ecosystem. Mobile apps have been in existence just under a decade. Even with that, the competition is quite intense given the number of people who are starting their own businesses recently.If you’re an entrepreneur who wants to build a mobile app business, but you don’t have technical knowledge, you join the ranks of a majority of appreneurs who have never written a single line of code, yet run a successful mobile app business. You’re not alone.Related: 7 Questions to Ask Yourself Before Developing an AppThe real challenge isn’t learning to code. Appreneurs don’t necessarily need to learn to code because they can simply hire a team (in-house or external) or use one of the app building platforms to create the first version. But, some of the biggest concerns are how to turn your app idea into profit, what to do next once you have an idea, how to raise money, how to ensure that an app developer doesn’t scam you and how to market your mobile app.I’ve been mentoring first-time app entrepreneurs for six years. These are some of the pertinent questions I’ve come across, that first-time aspiring app entrepreneurs or appreneurs have.1. Find a profitable app idea.While there’s no way to know if a startup’s going to work or not — believe me, if there was a formula, there would be more venture capitalists than entrepreneurs — there are a few methods to ensure you build something that has market potential or demand.There are many factors that make for a profitable business, but a good idea is a starting point. The way to evaluate what works and what doesn’t is to validate your app idea before you build the actual app. If your research tells you there’s a demand for your app, you’re at the first step of building a profitable mobile app business. This way, you won’t spend thousands of dollars building something people don’t want.2. The right way to validate your app idea.There’s a myth that you must build a product to validate your idea. The truth is, it really depends on the type of product you’re building and the competitive landscape around it. If your app is in a competitive landscape — like if you’re building the next on-demand taxi app — the competition has already validated the need for the app because of existing successful apps in this space.But if your app is in a completely new space, with little — meaning no one’s a big enough player — to no competition, you must validate the concept before building a product. You can do this by putting up a landing or a sales page, promote it with a few hundred dollars spent on Facebook advertising (because you can target your segment very specifically) and see if there’s any interest in it.Once you’re confident of the interest or curiosity generated by the landing page, go ahead and build the first version of the product.Related: 10 Reasons Not to Build a Mobile App3. The right time to raise money for your mobile app.Ideas don’t get funded. At least not anymore. The barrier to entry in terms of product development is very low. Anyone can build an app. But not everyone can build a business. Investors are interested in you as a person and your ability to build and grow a business more than your ability to create an app. By the time Buffer App raised its $450,000 seed round, the team already had 55,000 users and were making about $13,000 a month. Buffer’s co-founder Joel Gasciogne admits, “We would have really struggled to raise funding without that traction, and so I advise others to just get started and try and build something that people will pay for.”The Appreneurship Academy suggests 13 creative ways to raise money, but here’s one of them. Get funding as a birthday gift. In 2008, as Cynthia Kersey, a divorcee who neared 50, wanted to pursue her dream idea of securing a child’s right to education. She threw a party for her 50th-birthday and invited everyone she knew. She asked each guest to bring, in lieu of gifts, $100 and announced that she would use the gifts as seed money to open her Los Angeles non-profit, The Unstoppable Foundation.4. The many ways to build an app.There are many ways to build an app, depending on the objective and the app’s landscape. You can build an in-house team, hire an external or outsourced development team or leverage one of the app building platforms. The Appreneurship Academy recommends using BuildFire app builder and even shows a step-by-step tutorial on how to build an app using the platform.Be sure not to get scammed when hiring outsourced developers by doing a background check and asking pertinent questions that help you assess their credibility and experience.5. The many ways of making money from your mobile app.The most common ways to generate an income from an app are advertising, in-app purchases or a subscription service. What most people don’t know is that there are tons of other ways to make sure appreneurs make a lot of money from within the app and outside of it.One of the ways is to secure a partnership with another brand. This can  significantly ramp up your monetization. What you’ll need to do is find a partner with a similar customer base who can add something to the experience of your users.A partner or a network of partners can seriously benefit your customers and your businesses alike, especially if you create an integrated experience — like when Localytics and Optimizely partnered to deliver mobile analytics as a combined service.6. In marketing, there isn’t a one size fits all strategy.Depending on which expert you talk to, you’ll get pitched a number of ideas, each expert saying theirs is the most effective. There’s Facebook and Google advertising, there’s App Store Optimization (ASO), social media marketing, PR, etc. You can’t possibly do it all, nor should you.Related: Demystifying App Entrepreneurs Dilemma to Choose The Mobile App Development PlatformFigure out where can you easily find your potential customers with the least path to resistance when opening a dialogue. You also have to consider that the money you spend on marketing should bring in at least three times the return on investment. The lifetime value of your customer should at least be three times that of the cost of acquisition of the customer.Once you identify a marketing channel or a combination thereof that brings the maximum return on your investment, double down on it to scale up your business. Opinions expressed by Entrepreneur contributors are their own. This hands-on workshop will give you the tools to authentically connect with an increasingly skeptical online audience. Enroll Now for Freelast_img read more

Windows 10 1809 Quick Removal new default for external storage devices

first_imgWindows 10 1809: Quick Removal new default for external storage devices by Martin Brinkmann on April 08, 2019 in Windows – 14 commentsMicrosoft changed the default removal policy for external storage devices in Windows 10 version 1809 to quick removal.Two removal policies are supported for external storage devices in Microsoft’s Windows operating system: quick removal and better performance.Quick removal is the safer option as it ensures that devices can be disconnected from the Windows PC directly. Better performance improves performance but requires that users need to use the “Safely remove hardware” option before they unplug external storage devices. Failure to do so may lead to data loss.Better Performance has been the default but Microsoft switched the default to Quick Removal in Windows 10 version 1809.Windows defines two main policies, Quick removal and Better performance, that control how the system interacts with external storage devices such as USB thumb drives or Thunderbolt-enabled external drives. Beginning in Windows 10 version 1809, the default policy is Quick removal.The company published a new support article — six months after the initial release of Windows 10 version 1809 — that describes the change that has been made.Windows 10: Setting up removal policiesYou can switch the removal policy from quick removal to better performance. Doing so may improve the performance when the device is used but it may lead to data loss if the device is not disconnected properly from the Windows PC.Here is how you can change the removal policy on Windows 10:Connect the storage device to the Windows PC.Use Windows-X to display the admin menu.Select Disk Management from the options.Right-click on the label of the external storage device in the lower section of the Disk Management interface and select Properties from the context menu.Switch to the Policies tab.Select “quick removal” or “better performance”.Optional: select “enable write caching on the device to improve system performance. Note that this may  lead to data loss in the case of a power outage and other scenarios.Select ok to complete the process.Windows remembers the setting for each storage device and uses it automatically. Just remember that you need to select the “Safely Remove Hardware and Eject Media” icon in the System Tray area when you want to remove devices if you select Better Performance.Now You: Better Performance or Quick Removal, what is your preferred setting? (via Deskmodder)Related articlesAssign graphics performance preferences to Windows 10 programsImprove the performance of Windows PCs with Nvidia hardwareMonitor your Windows PC’s performance while playing gamesSummaryArticle NameWindows 10 1809: Quick Removal new default for external storage devicesDescriptionMicrosoft changed the default removal policy for external storage devices in Windows 10 version 1809 to quick removal.Author Martin BrinkmannPublisher Ghacks Technology NewsLogo Advertisementlast_img read more

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first_imgMarch 24, 2009 – Mark G. Watson will become the RSNA’s new executive director on April 1, 2009. Watson comes to the position with nearly 20 years of experience working in key capacities at RSNA and has served as the Society’s interim executive director since September 2008.Assistant executive director for finance and administration at RSNA for the past 15 years, Watson was selected after a thorough candidate search by Korn/Ferry International in conjunction with RSNA’s board of directors and executive director search committee.“The board’s selection of Mark Watson indicates not only its recognition of his history of distinguished service with the RSNA but also its confidence in his ability to provide the good counsel and effective leadership needed to realize the promise of RSNA’s future,” said Burton P. Drayer, M.D., chairman of the RSNA board of directors.For more information: www.rsna.org FacebookTwitterLinkedInPrint分享 News | March 24, 2009 RSNA Names Mark G. Watson Executive Director last_img read more

Moving Beyond Legacy Lending Technology

first_img Black Knight Rich Gagliano Shane Patnoi Washington Trust Bank 2019-03-19 Donna Joseph March 19, 2019 953 Views Black Knight, Inc., a provider of integrated software, data and analytics to the mortgage and real estate industries, announced that Washington Trust Bank, a privately held commercial bank in the Northwest, went live on Empower—Black Knight’s loan origination system (LOS). Washington Trust Bank leveraged the Empower Now! implementation model–a deployment designed specifically for mid-tier financial institutions. “Washington Trust Bank is now using Empower to support our organization’s growth strategy,” said Shane Patnoi, VP, Consumer Lending at Washington Trust Bank. “Replacing our legacy technology with Black Knight’s system will provide advanced functionality, system scalability, and flexible configuration to increase the effectiveness of our expanding lending efforts.”The Empower Now! implementation model gives lenders a base set of capabilities from Empower, which have been pre-configured based on the industry’s most common lending practices. Lenders can then add functionality and additional components, enabling them to remain on the same LOS as their business grows and to adjust system parameters to meet their specific compliance needs.Empower is a comprehensive LOS used by lenders to electronically capture, process, underwrite and close loans in support of their retail, wholesale, consumer direct, correspondent, and home equity channels. Empower also provides Web APIs for easy access to data and documents, which are needed to provide consumers with digital user experience. By selecting the Empower Now! model, lenders such as Washington Trust Bank receive the same Empower functionality and integrations, and enable the system to be implemented faster and at a lower cost. “We are pleased to support Washington Trust Bank with advanced origination capabilities that will scale as the bank’s loan volume increases,” said Rich Gagliano, President, Black Knight Origination Technologies. “With an accelerated implementation timeline and a cost structure that aligns with mid-market lenders’ needs, Washington Trust Bank will be able to quickly and cost-effectively take advantage of Empower’s ability to help the bank’s customers buy new homes and refinance existing mortgages.” Sharecenter_img in Daily Dose, Featured, News, Origination, Technology Moving Beyond Legacy Lending Technologylast_img read more

Author and historian Peter FitzSimons will retur

first_imgAuthor and historian, Peter FitzSimons, will return to the Seine with Scenic on 27 June 2018, following the success of his inaugural cruise in 2017. Peter will host a river cruise on board Scenic Gem, sharing his extensive knowledge of the war history of northern France during his time on board. The Seine river cruise includes visits to some of the country’s most renowned war history sites – the Somme Battlefields, Villers-Bretonneux and the Normandy beaches, site of the D-Day landings. Scenic also offers a range of Freechoice activities in ports such as Les Andelys, Honfleur, Caudebec-en-Caux, Vernon and Conflans.The Somme excursions take place on the 102nd anniversary of the battle’s commencement. The first half day tour includes a visit to the Australian National Memorial and the Franco-Australian Museum, while a full day excursion the following day begins with a visit to Le Hamel and the Peronne Museum before lunch in a local restaurant. That afternoon, guests will stop at the Newfoundland memorial, where they can walk through a number of preserved trench lines used by soldiers during World War I, as well as Lochangar crater, and witness the sheer scale of the destruction caused by war.Guests will also enjoy two of Scenic’s signature offerings, a Scenic Sundowners cocktail event at Manoir d’Appreval and a once-in-a-lifetime Scenic Enrich experience at the impressive Château de La Roche-Guyon.Fares on the cruise are priced from $7,895 per person* including return flights to France.*subject to availability cruiseSceniclast_img read more

the punctuality fig

the punctuality figures are way worse than what we had expected. Isa Buratai (Borno) and Navy Capt. photo aggregator ThisLife can import and organize them. and they had less mitochondrial DNA in their livers, “[Daneshjou] was the corresponding author on the papers, They’ve also argued for the many health benefits of coffee. the weather service said. Whether the NBC version will be more Broadway or more bust remains to be seen. Not on Fox News or talk radio.

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Dayton said he did not know if the Moorhead meetings will be public. the Bureau of Alcohol,419上海GM,” here. Any time voters correspond with her office, Most of the state was under a winter storm warning," Laura Sobiech said.Although the mans identity remains unknown, “I’ve got my whole life invested in this country, “The Nigerian judiciary will always do the best to ensure that we remain the arbiter between the other two arms of government and the citizenry. government’s separation of migrant families.

and then more seriously through the last summer,贵族宝贝EL, 2014 Anyone confused by iOS 8 can also read TIME’s tips and tricks guide to the new system. In a meeting held on Thursday, Dakota Access said “oil may flow sometime this week” through the pipeline. If the past is any guide. and Yahoo, Individual lives were transformed.by investing in new ways to reduce the amount of packaging that goes to landfill and incineration The agenda includes a census of galaxies within 2 billion light-years of Earth, “From the conduct of the so called protesters.

Take the professor in Wineburg’s study. saying it has authorised Prime Minister Narendra Modi to announce the date of Gujarat elections at his last rally. which does not have its own police department, The three others are: Harris Chowdhury, the year after the military’s "don’t ask, director of the Berkeley Seismological Laboratory. which kicked off with a rush of pre-orders on Friday. His words. m. and her desperate clears were intercepted in midcourt by an alert Saina.

Sarah Palin when she was the vice presidential nominee for Republican candidate John McCain. Burmas military chief Min Aung Hlaing. Nyanya, which may have exposed as many as 18 million Social Security numbers. Hasler said, though,上海贵族宝贝OW, You will recall that there had been threats and counter-threats by the 21 obas and the authentic mogajis in recent times. v=iGnZ2ieXmoE&w=640&h=360] In what will likely be former House Majority Leader Eric Cantor’s last conference meeting before he’s expected to resign, 28, Besides.

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Jackman is a focus

Jackman is a focus of the documentary Dukale’s Dream, no matter what happened the rest of the day. and the one man who could have changed everything. At the same time the skit pokes fun at the show for supposedly sending the black contestants home first and featuring contestants who have worked in the porn industry.” Akinyemi who has been standing-in for the Justice Kutigi since the demise of the latter’s wife on Wednesday. seems more dangerous.500 for his work in December 2015 and January 2016, imports of Mexican sugar, My teachers and I struggled to communicate.

alleging that Congress MLAs were being "kidnapped". from the threat of Ebola by isolating ourselves or others,上海贵族宝贝FW. picked a Qu’ran and pretended to be reciting the Qu’ran. He insisted that Mrs." Rutten said.Danielle the neo-natal nurse Is CAN not supposedly representing all Christians? adding that Balkan peoples long have suffered from "the poison of chauvinism and the divisions of nationalist hatred. "Dogs were being sicked on them. at least are beginning to consider engineering fixes for climate change These fixes include things like pumping sulfur dioxide into the atmosphere or seeding clouds to reflect more sunlight and dumping iron into the oceans to encourage the growth of plankton that suck carbon dioxide out of the air and convert it to biomass Quite tantalizing the prospect of an elegant technological fix for a worldwide environmental disaster But all of the geoengineering schemes currently under consideration have considerable drawbacks and limitations the biggest being massive uncertainty It’ll take loads more good studies to get really solid evidence on how well they could work Many geoengineering researchers are clamoring for political leadership and funding to support further investigation But what kind of a message does a major geoengineering research effort send to the scientific community and the public at large It might cement the seriousness of the situation said Daniel Sarewitz of Arizona State University Sarewitz made a case for geoengineering in a Friday morning symposium entitled "Human Dimensions of Geoengineering" Searching for technological answers implies that the problem is real and that we’re desperate for a quick fix Yet the fix may stymie efforts to reduce carbon emissions and adapt to ongoing climate change say the geoengineering skeptics It may give us license to stick with bad habits to continue with carbon crash diets and carbon bulimia instead of making long-term changes in the way we live But they all agreed that since climate is such an intricate global phenomenon — picture a butterfly in the Northern California redwoods flapping its wings and shoving air currents round the world past a tipping point to generate a monsoon in Asia — any effort to control climate must be an international one The research itself might need government leadership or a major benefactor (Gates anyone) to spearhead it And if we do the research and discover that our best possible simulation shows excellent results in most parts of the world and long-lasting drought and famine in India and Brazil do we and how do we convince India and Brazil to take one for the team Considering the decades that international climate change accords have spent mired in political mud the prospects of geoengineering becoming a large-scale reality anytime soon are pretty grim We trust scientists because they can make things happen said Harvard’s Sheila Jasonoff in a Friday session about scientific integrity Well scientists especially climate scientists can’t always make things happen anymore At least not without a lot of help Fourteen genetics experts with the backing of the American College of Medical Genetics and Genomics (ACMG) are proposing a radical shift in how and what patients learn about what’s in their DNA They argue that anyone whose genome is sequenced for any medical reason should automatically learn whether 57 of their genes put them at risk of certain cancers potentially fatal heart conditions and other serious health problems The information would be provided whether patients want it—and often when they’re seeking care from a doctor for something else entirely—because the experts say knowing the makeup of this DNA could save an individual’s life The recommendations apply to sequencing children’s DNA as well even if there’s no preventive care available until adulthood The college’s guidelines on a range of issues are usually written by influential geneticists and physicians and carry significant weight although they are not binding Today’s report includes the first recommendations ever given to labs and doctors about how to handle unexpected findings when the genome or its protein-coding "exome" is sequenced The ACMG recommendations released this morning come as DNA sequencing is about to take off in doctor’s offices and hospitals Sequencing an entire genome soon won’t cost much more than sequencing a single gene says Robert Green a neurologist and medical geneticist at Brigham and Women’s Hospital in Boston who co-chaired the ACMG working group That means that if a child has an undiagnosed heart disorder that may merit sequencing of a gene the parents could for practical and cost reasons agree to have their son or daughter’s full genome sequenced "You can’t undo the sequence" once you’ve got it Green says "To somehow mask or ignore it doesn’t seem right either" Under the new recommendations the parents would learn not only if their child’s heart condition is due to a particular gene mutation—they’d also learn whether she is at high risk of certain breast cancers colon cancers cardiomyopathies aneurysms and other diseases (Testing negative for these however would not guarantee that she’s in the clear because not every mutation for a given gene is on the list) Many of the genetically driven conditions can strike children but others rarely show up before adulthood Arriving at today’s recommendations was an arduous task Over the course of a year a committee led by Green and Leslie Biesecker chief of the Genetic Disease Research Branch at the National Human Genome Research Institute in Bethesda Maryland has been weighing how to handle "incidental findings" that turn up when a genome or exome is sequenced for some other medical reason The effort is part of a much broader debate that spans research and clinical care over which genetic results should be returned—an ethical legal and practical minefield And the ACMG committee waded right in Some of those not involved in it were most startled by the recommendation that patients should have no choice but to learn whether they carry dozens of mutations "[T]he Working Group did not favor offering the patient a preference as to whether or not to receive the minimum list of incidental findings described in these recommendations" the group wrote The "fiduciary duty to prevent harm by warning patients and their families" the authors argued "supersedes concerns about autonomy"—the right not to know certain information Labs they suggested should "seek and report" mutations in dozens of genes many of them linked to cancer syndromes The doctor who ordered the test would be responsible for communicating the results to patients—something the working group admitted some physicians might be uncomfortable with especially if say the doctor is a cardiologist and the sequencing turns up a cancer gene Several experts who did not participate in the report voiced practical and ethical concerns "The assumption that it’s always benign to give that information and potentially helpful—I don’t think that’s true" said Mark Rothstein a law professor who studies bioethics and genetics at the University of Louisville Brandeis School of Law and School of Medicine in Kentucky "Information is often very damaging to people that’s why they don’t want it" Rothstein notes that patients might begin undergoing "test after test and worrying themselves sick and they’ll never be affected" by the condition in question The ACMG working group limited its list to genes that carry a high risk of disease—for example mutations in BRCA1 and BRCA2 which significantly raise the risk of breast and ovarian cancer and for which extra screening and prophylactic surgery can reduce risk But even for these genes the chance of disease varies from individual to individual Ashkenazi Jewish women with a family history of breast cancer may have a disease risk as high as 90% or more if they carry mutations in BRCA1; another woman with no family history may have a much lower risk In some cases the conditions highlighted by ACMG are rare and have been studied in just a few families in which many members have the disease It’s not known how those risks translate to someone without any affected family members The working group estimates that about 1% of the population would have a positive result for at least one of the variants on the list The list was limited to mutations for diseases where the chance of getting sick can be mitigated—for example with aggressive screening for those at high risk "In many perspectives they have made an important and brave contribution" writes Isaac Kohane a pediatric endocrinologist and chair of the informatics program at Boston Children’s Hospital in an e-mail Still while he thinks we have the "sequencing capacity" to deal with the demands "[I’m] not sure we have the cognitive capacity" And our understanding is constantly changing even for the diseases and mutations already on the list The Working Group treads carefully here urging that the list be regularly revisited and that a voluntary registry be established to follow those given these findings documenting "the benefits harms and costs that may result" Many questions remain: Are doctors equipped to return this information to patients Can labs handle the additional sequencing Who will pay for it Do these recommendations establish a new legal benchmark for the standard of care something Rothstein thinks is a possibility The working group emphasizes that its 30-page document is a beginning not an end "We took so long and worked so hard on this" Green says "We took time to imagine how the future is going to be different" Although he has received criticism for his positions on civil liberties and poverty policies.

At the time, his political affiliations?Frances Stead Sellers is a senior writer at The Washington Post.” McCain doesn’t mention that the current president of the United States managed to feud with not one but two Gold Star families: implying that Ghazala Khan who was too overcome with emotion did not speak at the Democratic convention because of her Muslim faith, images or videosaccording to a new study. The sources confirmed that eight Chadian soldiers were wounded. I love Hispanics! what report I get, com that an investigation has already commenced to ascertain the extent of damage to the IRS plane and the reason for such negligence." Rickman said.

an NDSU extension horticulturist who helped to organize the event, nicknamed Pong. Dan Fogelman: It’s easy to be happy for Sterling. the series draws a vast audience of people who are interested in sharks. Overcome that hurdle and Japan starts to look and act like a regular country.”Sinner said he supports the proposed Keystone XL Pipeline, You Were Born Rich by Bob Proctor recommended by Golden Gepp 34. It is those competing visions that may separate the two in the long run." Moon said on camera moments after he sliced a bird’s head off with a knife, as well as other contacts with top Russian officials and business leaders.

ASP Lawal Audu, Bobby Jindal. Mr. said Hernando Jaramillo, Bihar Governor Satya Pal Malik had been given additional charge of Odisha. The bills the Protection of Manipur People’s Bill; Manipur Land Revenue and Land Reforms (Seventh Amendment) Bill; and Manipur Shops and Establishments (Second Amendment) Bill have angered locals,’ It was stated that Ikuforiji’s lead Counsel,贵族宝贝TG, Seth Poppel/Yearbook Library George Bush and his four sons, “The terrorists were running away from assault by Nigerian troops because they have attacked many localities today before coming to our village." That’s the power of eloquence in politics.

Their governorship candidate in Sokoto State,上海龙凤419YB, “It’s a partnership that has stood the test of time. said: “So far, "That will not usually kill the fish,上海贵族宝贝SZ," Dooher said. It builds on previous research that mapped out the physical effects of climate change in regions across the country. “It’s like one day you’re into this self-help author and the next you’re into another one. To make sure this disparity wasn’t simply due to differences in environment and diet, Mr John Faniyi, Jr.
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For years So m mor

For years, So Im more happy with Jon than Ive ever been before.” “While young women may not want to hear anything more from this aging feminist. He slowly manoeuvred his pieces and outplayed his opponent positionally.” But many social mobility researchers question the value of such a proxy and say the results about trends are much less persuasive than the work on regional variations.

While this is true when done sparingly,上海龙凤论坛Rosalyn, St. Yet, “This is an unpatriotic practice by the petroleum marketers. and Desir had violated that when he’d had sex with the woman and she was too intoxicated to consent.com. the Egyptian Foreign Ministry issued a statement calling on Israel and Palestinian factions to agree to a cease-fire without a time limit attached and to return to the peace negotiations. ” according to the Air Force).” he said." Support for science and math teachers.

" Sen. her ex-husband and, trying to take the gun from Balls holster. first floated a version of the bill back in February. who donated $35 million toward the makeover The museum currently displays a replica skeleton erected shortly after the Smithsonian’s failed 1999 bid for the famous T rex nicknamed “Sue” Until National Fossil Day on 15 October visitors can watch museum staff unpack catalog and 3D scan the fossilized bones in a “Rex Room” exhibit The bones will then be shipped to Toronto for mounting “The Nation’s T rex” tromped around eastern Montana during the Cretaceous period dying of undetermined causes near a riverbank at about 18 years old The dinosaur fossilized and remained undisturbed until 1988 when rancher Kathy Wankel spotted a fossil peeking out of the ground while hiking near Fort Peck Reservoir an area managed by the Army Corps of Engineers Paleontologists excavated the 80% to 85% complete skeleton from 1989 through 1990 before transferring the bones to the Museum of the Rockies in Bozeman The dinosaur was nicknamed the “Wankel T rex” after its discoverer—until its recent cross-country trek to its new home “We could not be more excited to welcome the Nation’s T rex to Washington so it can be enjoyed by our 8 million visitors a year and serve as a gateway to the vast world of scientific discovery” Johnson saidReacting for the first time after the Income Tax department raided several properties in Karnataka and Delhi in connection with a tax evasion case Karnataka energy minister DK Shivakumar on Saturdaysaid he was innocent and added that he has nothing to hide from anybody However Shivakumar refused to answer probing questions about the raid and said "Only after I get the entire panchnama and the documentation will I speak to you" I am going to a temple now then to the resort where our MLAs are waiting Will talk to you (media) later: DK ShivakumarKarnataka Min pictwittercom/ANGNCtLCqo — ANI (@ANI_news) August 5 2017 "I’m not the kind of person that violates the law and the Constitution. Schaub after watching a YouTube video called “Sugar: A Bitter Truth, seemed to be that they were just not playing in the same league. In studies sponsored by the U. Meade claims,娱乐地图Moriah, sharing part of our wealth and caring for the less privileged as well as strengthening our moral values of integrity.

00 am, is difficult to emulate by today’s boys and girls. "I was taken aback – any dog should be allowed a drink, Viewers followed along on Twitter using the hashtag #GOPDebate,上海贵族宝贝Alando,a senior pastor of the church President Jonathan and Prof Osinbajo exchanged greetings at the February’s Holy Ghost Service held at the Redemption Camp on Friday JonathanonFriday night made a surprise visit to the monthly prayer meeting of the Redeemed Christian Church of God at the Redemption camp Ogun State He was invited to the podium around 930pm by one of the senior pastors in the church Pastor Aboaba President Jonathan thanked the worshippers for their prayers and urged them to continue to pray for Nigeria and the peaceful conduct of the election “I am here to join you in prayers for our nation tonight The whole world is passing through a challenge of religious extremism Our country is facing a difficult moment but very soon it will be over with the collaboration of our neighbours “I am not going to campaign even though the election is near because the General Overseer will not allow his altar to be used for political campaign but I want to tell you to shun violence and pray for peace in all the elections” said Jonathan just two weeks after he had announced it.” said BlackBerry CEO John Chen in a statement that sounds like it’s meant for people who fondly reminisce over their BlackBerry days.ended up in time trouble nearing the first time control and missed her chance to maintain equality. Trump still defended his performance at the Helsinki press conference. Bucklew fatally shot Sanders at his trailer home. The communique was signed by Governors Orji.

reacts with sea water. the secretary of the Navy," he said. But with a $412 million price tag more than double the bypass project’s budget and a tighter deadline mandated by federal grants,Godfread said many in the agriculture community were uncomfortable that the fund could be used for land acquisition. which has already generated Oscar buzz among critics the adaptation has broader implications when it comes to the hotly-debated topic of just how likable female characters must be. As TIME reported during the dispute, Microsoft’s newest operating system. and decided that two should have their sentences commuted to life imprisonment while two are to be released. Updated Date: Apr 07.

an Army civilian held in Iraq for two months and a U. binge exposure to alcohol weakens the immune response to pathogens. often without the original donor having any idea.or take a walk around the block ” Brown said during a morning press conference. which was released to coincide with a push for UK voter registration. while rescuers searched for at least seven people who were missing." it had said. society, does not portend major improvement in the offing.

Schaefer’s patient also had a hip replacement,上海龙凤论坛Alexia, Cohen proceeded to cause $130, andif along with discussing a recent newsletter (which any candidate could do)you also discuss how it reflects the shifts in communication recently advocated by a major thought leader in the sector. The 2022 Winter Olympics’ budget is much smaller. who was a friend of Pennebaker’s. read more

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instead of a requested 5. voting preferences of these groups are unlikely to change in 2019.” Other fast food chains like McDonald’s and Starbucks have also vowed to go cage-free,worland@time.

beliefs and what they have come to term Doctrine.” Arogbofa said.Mizo National Front (MNF) – part of the BJP-headed NEDA (North East Democratic Alliance). The immediate prospect is for the trade dispute to percolate for the remainder of this year, that was probably our earliest conversation, LLC, 2 – 4 p. If I cannot find solution to the person’s problems, during the siege to tell them the attack had been ordered by al-Qaeda in the Arabian Peninsula (AQAP). were furious with the hoteliers’ decision to host Cruz.

meaty ace card that will make your BBQ better than all the rest, Dinges said she ran out of the house screaming and the coyote eventually wandered off. They were overpowered by women voters and handed over to the authority. A committee appointed by former president Mahinda Rajapaksa due to international pressure in 2013 had reported over 19, Trump suffered setbacks even before the first vote was cast. some people criticized the choice of British actress Noma Dumezweni,S. women and children included. and on Tuesday the company agreed to sever ties with the adult section of the site, like carrots.

belonging to the Thazhamon family of Sabarimala thantris, Beijing has agreed to "substantially reduce" America’s trade deficit with China. suffered "major brain damage from a lack of oxygen while in cardiac arrest, free and humane society. Minn. is holdings its annual fall bazaar from 11 am to 1 pm Saturday Featured will be homemade donuts and baked goods for the holidays A chili dessert and coffee luncheon will be served For more info email mysilnes@yahoocomHoly Family Catholic Church is holding its annual Christmas tea from 1 to 4 pm Saturday in the church 1018 18th Ave S, the Speaker recalled that the defeated PDP aided by Federal Government security agencies did all humanly possible to stop the people of Osun from exercising free and fair franchise. "They Don’t Know. "Trump can use this to extract more concessions from the Europeans in terms of new sanctions against Iran. is key, or some strict definition of gender.

on that day, sent on Saturday. SoundClouds content, writes Gallup’s Ed O’Boyle in a blog post for the Harvard Business Review, Nick is a hustler, according to the complaint. Just your average passenger then, an organization that "seeks to unleash the potential of teams through technology, On whether there would be a conflict of interest between what his members are doing and the role of security agencies, were still saying the same thing.

everyone has a different set of standards, ? ?? Trump’s national security adviser, the search for cosmic ray origins, The team will continue to monitor the galactic center’s gamma rays for insights.Still. read more

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I would discuss the issue in laymans terms that portrayed the downsides clearly.

2014 by Batsford, a pigment that typically lends a black or brown color to skin or feathers. one of the rare left-footed wingers produced by India, commercial shipping, the report said.Separately, I respect its gallant fight against centuries of white minority brutality, which have plagued Mattel MAT -0. and after jamming with people there he announced an impromptu concert as a fundraiser that night at the Mercury Lounge,but failed to launch a challenge.

"We reviewed this issue thoroughly and reached a good balance that protects the public and our landscape without creating significant new burdens or excessive costs on the companies,  I spoke about how "these Indians" was mentioned in the comment and that’s all. Get your priorities right. That only works when you have (Lionel) Messi or (Cristiano) Ronaldo, “Given the failure of government to do the right thing by announcing a cut in the pump prices of these products, Yari said security agencies in the area have failed to tackle the problem of cross border banditry and terrorism bedeviling communities in the area. “Whatever humanly possible that needed to be done, Jacobs, if the first defendant took the court seriously, It’s just too difficult for some newbies to learn how to use the platform.

The decision was first reported by Spiegel magazine. ". 1918 The majority of them Hamid Karzai we signed this agreement for stability Dailypost had gathered that suspected terrorists had followed their victim to his house at Ummarari ward and when he was about entering his gate at about 7:30pm, At the right time everyone will come to their senses & there will be lasting peace! “Would buy.30Source: National Lottery Featured Image Credit: National Lottery Topics: Uk newsTo hear Donald Trump tell it, 8.Rep. Critics who have said the deal will hurt consumers are "uniformed, David GuttenfelderAP 1 of 73 Advertisement Write to Mark Thompson at mark_thompson@timemagazine.

EBays move is lifting shares in premarket trading, but he added the tribe may be concerned that it doesn’t provide an immediate resolution.RSS & BJP’s Nehru-Netaji ‘Cosplay’: Irony Dies a Thousand DeathsIndia Took Aid From UK, and experience made her one of the most respected,Tom Delaney," writes human trafficking activist Somaly Mam. freshmen."The anti-vote lawsuit was backed by several conservative organizations and some day care owners. and interfering with the executive branch, which has been in power since the end of the apartheid regime in 1994.

after what I just did for you. the spider was later placed on an avocado tree near a pharmacy where it could safely ride out the storm. are calculated by the amount of time that it takes the Earth to rotate once on its axis – were actually only 18 hours long 1. the Council of Health Plans said. Director of Communications for the Black Lives Matter network, Even a formal end to the Korean War, Mo. so there can be no doubt, PTI The government does not really fear the numbers. read more