New blood test developed for early diagnosis of ovarian cancer

first_img Source:https://www.adelaide.edu.au/news/news103642.html Reviewed by James Ives, M.Psych. (Editor)Nov 19 2018Research on a bacterial toxin first discovered in Adelaide has led to the development a new blood test for the early diagnosis of ovarian cancer – a disease which kills over 1000 Australian women and 150,000 globally each year.The new blood test has the potential to dramatically improve early detection of the disease, although it will require further testing before it is available for clinicians.A research team from the University of Adelaide and Griffith University have been studying the interactions between the toxin and an abnormal glycan (sugar) expressed on the surface of human cancer cells and released into the blood.Related StoriesStudy: Nearly a quarter of low-risk thyroid cancer patients receive more treatment than necessarySpecial blood test may predict relapse risk for breast cancer patientsUsing machine learning algorithm to accurately diagnose breast cancerThe team has now engineered a harmless portion of the toxin to enhance its specificity for the cancer glycan and used this to detect it in blood samples from women with ovarian cancer.A paper published this month in Biochemical and Biophysical Research Communications has shown that the new test detected significant levels of the cancer glycan in blood samples from over 90% of women with stage 1 ovarian cancer and in 100% of samples from later stages of the disease, but not in any of the samples from healthy controls.”Ovarian cancer is notoriously difficult to detect in its early stages, when there are more options for treatment and survival rates are better. Our new test is therefore a potential game changer,” says Professor James Paton, Director of the University of Adelaide’s Research Centre for Infectious Diseases.Professor Michael Jennings, Deputy Director of the Institute for Glycomics at Griffith University, said: “Detection of this tumor marker may also play a role in a simple liquid biopsy to monitor disease stage and treatment.”The team is currently seeking scientific and commercial partners to further test the technology with larger numbers of patient samples and to adapt it for mass screening.last_img read more

Madras HC stays online sale of medicines till November 9

first_imgSHARE courts and legal Madras HC e-commerce and e-business October 31, 2018 Published on The Madras High Court on Wednesday granted interim injunction restraining online sale of medicines till November 9. Justice R Mahadevan passed the interim order on a plea moved by the Chennai-based Tamil Nadu Chemists & Druggists Association seeking a direction to authorities concerned to block links of websites that selling medicines online. The court directed the Centre to file a counter and posted the matter for further hearing to November 9. According to the association, though online shopping might be convenient to consumers, purchasing medicines from unlicensed online stores can be risky as they may sell fake, expired, contaminated, unapproved drugs or otherwise unsafe products that are dangerous to patients and which might put their health at risk. Moreover, laws for pharmacies in India are derived from Drugs and Cosmetics Act, 1940, Drugs and Cosmetics Rule, 1945 and Pharmacy Act, 1948. These laws were written prior to arrival of computers and India does not have any concrete laws defined for online sale of medicines, the association submitted. Though various amendments have been made to the Act no provision has been made to utilise information technology for sale of medicines online, it said. COMMENTS COMMENT medicine SHARE SHARE EMAILlast_img read more

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Choose slow music background to improve store turnover

consumers usually into the store shopping will often encounter some stores play music, to provide consumers with a good shopping environment. If you want to improve the turnover so you can choose to play music in the choice of precision, combined with the characteristics of the store to choose the appropriate music, so that consumers are willing to stay longer in the store.


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