Green Pond draw, Dinthill win

first_img Irwin 1 Green Pond 1 Maldon 0 St James 3 Knockalva 1 Frome 4 Lacovia 2 Maggotty 1 Munro 1 Newell 1 Cross Keys 1 Manchester 5 Belair 0 BB Coke 2 deCarteret 0 Mile Gully 1 Lennon 5 Thompson Town 0 Edwin Allen 3 Claude McKay 1 York Castle 0 Steer Town 0 Ocho Rios 0 Marcus Garvey 1 Brown’s Town 2 Aabuthnott Gallimore 1 Charlemont 2 Guy’s Hill 2 Dinthill 3 Bog Walk 1 Winston Jones 0 Denbigh 2 Porus High 0 Garvey Maceo 1 Foga Road 0 Glenmuir 3 Today’s games Robert Lightbourne vs Yallahs Paul Bogle vs St Thomas Tech Seaforth vs Morant Bay Kemps Hill vs Old Harbour Vere Tech. vs Tacius Golding Brimmervale vs St. Mary High St Mary Tech. vs Iona High Christiana vs May Day Alston vs Spalding Bellefield vs Holmwood Little London vs Grange Hill Maud McLeod vs Manning’s Godfrey Stewart vs Petersfield Herbert Morrison vs William Knibb Holland vs Spot Valley Muschett vs Cedric Titus Central vs Bustamante Fair Prospect vs Happy Grove Oracabessa vs Port Antonio Tacky High vs Horace Clarke High WESTERN BUREAU: A Heavy and persistent downpour made the Zone A ISSA-FLOW daCosta Cup football game between Irwin High and Green Pond at Irwin a wretched experience, but in the end the 1-1 draw, according to the coaches, was a fair result. The rain had caused the field to be in puddles in certain sections by the scheduled kick-off time approached, and to make matters worse, it also accounted for the late arrival of the referee’s assistants. When they did arrive, the decision was taken to play two halves of 40 minutes each, as kick-off was already 40 minutes late. Forward Evardo Chambers missed two chances, but scored Green Pond’s all-important goal in the 37th minute. With their new coach, the experienced Anthony ‘Follies’ Williams, pulling the strings, Irwin went all out for the equaliser. It came with seconds left, following a mad scramble inside the six-yard box, which resulted in the ball rolling over the goal line and the referee signalling goal, with Green Pond’s goalkeeper, Kemar Ogle, left writhing in pain. He was eventually substituted and the game eventually ended in a 1-1 draw. “This is a work in progress for us,” stated Irwin’s coach Williams. “It was a spirited performance from the players and the wet conditions didn’t make it any better for us.” He added: “There is potential here and we are taking it match by match to see how far we can actually go. But I am all night with this draw, which could have been worse for us.” For Daley, however, it was two points lost. “We should have won the game hands down. We missed several chances to easily secure three points. But I will take this,” he said. Meanwhile, St James High joined Cornwall College at the top of Zone A with three points, after their 3-0 victory over Maldon, who are in last place in the zone. In Zone K, last year’s beaten finalists, Dinthill Technical, began their campaign with a 3-1 win over Bog Walk. Yesterday’s resultslast_img read more

Fans claim Hazard is best player in Premier League during hat-trick performance

first_imgStill can’t believe that people don’t think Eden Hazard is the best player in the league.— ¹⁰ (@ClinicaIEden) September 15, 2018 1 When he starts, he scores. Eden Hazard in 2018-19:🔵 🅰️🔵 🅰️🔵 ⚽️🔵 ⚽️ ⚽️🅰️ ⚽️🔵 ⚽️#cfc— Kristof Terreur 📰 (@HLNinEngeland) September 15, 2018 He then added a third from the penalty spot to complete his hat-trick in the second half.Sol Bamba gave the Bluebirds a shock lead at Stamford Bridge before Hazard turned on the style.The Belgian has now scored five goals in three games since returning to the team’s starting XI against Newcastle.You can read the best reaction from social media below. Can’t deny it, Eden Hazard is world class and currently the best player in the league at the moment.— – (@AnfieldRd96) September 15, 2018 Tottenham issue immediate ban to supporter who threw cup at Kepa smart causal England’s most successful clubs of the past decade, according to trophies won EDEN HAZARD, MY LORDWe. Are. Not. Worthy.— Alex Goldberg (@AlexGoldberg_) September 15, 2018 punished possible standings silverware Premier League Team of the Season so far, including Liverpool and Leicester stars Every current Premier League club’s best kit from the past decade REVEALED Boxing Day fixtures: All nine Premier League games live on talkSPORT shining center_img REAL DEAL tense Which teams do the best on Boxing Day in the Premier League era? REVEALED Latest Chelsea News gameday cracker Eden Hazard is by far the best player in England If you disagree than you’re wrong— . (@OfficialCheIs) September 15, 2018 Full freedom Eden Hazard under an attack minded manager was always going to be a problem.. every sane Chelsea fan predicted this. But people called him overrated because he didn’t put up ridiculous numbers in defensive systems. You’ll see ridiculous numbers now.— َ (@HazardEdition) September 15, 2018 How the Premier League table could change after the Boxing Day fixtures Real Madrid ‘offer’ Isco to Chelsea in bid to ‘make room’ for Tottenham star Green reveals how he confronted Sarri after Chelsea’s 6-0 defeat at Man City Gotta say Eden Hazard is a top top footballer. He had a very strong World Cup campaign, and his start to the season under Sarri has just been brilliant. Lovely to watch.— Seleção Brasileira (@BrazilStat) September 15, 2018 Eden Hazard was instrumental for Chelsea against Cardiff Eden Hazard put on a magnificent performance during Chelsea v Cardiff on Saturday.The 27-year-old attacker bagged two goals in the first 45 minutes to pick his side up after they conceded early on. Where Ancelotti ranks with every Premier League boss for trophies won last_img read more

Banned weightloss drug could combat liver disease diabetes

first_img Sign up for our daily newsletter Get more great content like this delivered right to you! Country A drug the U.S. government once branded “extremely dangerous and not fit for human consumption” deserves a second chance, a study of rats suggests. Researchers report that a slow-release version of the compound reverses diabetes and nonalcoholic fatty liver disease (NAFLD), an untreatable condition that can lead to cirrhosis and liver cancer.Diabetes has already become an epidemic. And up to 30% of people around the world may have a lesser known but related metabolic illness, NAFLD, in which lipids—the family of molecules that includes fats—amass in the liver. Although the extra fat often causes few problems, about 10% to 20% of people develop nonalcoholic steatohepatitis (NASH), a serious illness in which inflammation and scarring can provoke cancer and liver failure. So far, there are no approved drugs for treating either condition. “This is one of the biggest unmet needs in medicine today,” says hepatologist Rohit Loomba of the University of California, San Diego.To address that need, endocrinologist Gerald Shulman of the Yale University School of Medicine and colleagues proposed resurrecting a drug with a dark history: 2,4 dinitrophenol (DNP). Originally used as an industrial chemical and explosive, the compound captured researchers’ attention after French munitions workers were exposed to high levels of it during World War I. One frequent consequence of this exposure was weight loss—although another consequence was sometimes death. After further research suggested the compound spurred obese people to shed pounds, drugmakers in the 1930s included DNP in diet pills that were available without a prescription. The U.S. Food and Drug Administration (FDA) banned the compound at the end of the decade, however, because it caused side effects such as cataracts and was responsible for a handful of deaths. 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Required fields are indicated by an asterisk (*) Despite its bad reputation, DNP does have some virtues. By altering the activity of mitochondria—the powerhouses that provide cells with energy—it forces the body to burn fat. It provides other metabolic benefits as well. For example, people with NAFLD or diabetes typically have insulin resistance, meaning that their cells don’t respond normally to the hormone that controls blood sugar levels. However, when Shulman and colleagues fed DNP to rats, they found that the drug boosted the animals’ insulin sensitivity.The researchers decided to design a safer version of DNP that would retain its benefits. First they tried to limit the effects of the drug by creating a version that is active mainly in the liver. In a study published in 2013, the researchers demonstrated that this version of the drug was about one-tenth as toxic as standard DNP. Moreover, the targeted drug reduced fat buildup in the livers of rats that had NAFLD and improved the animals’ insulin sensitivity.But the researchers thought they could do even better. In their new study, they packed the original form of DNP into a pill that slowly dissolves and releases the drug over 12 to 24 hours. This strategy reduces the amount of the drug in the bloodstream. When fed to rats that devour a fat-laden diet and develop their own version of NAFLD, the slow-release drug slashed their liver lipid levels by about 90%, Shulman and colleagues report online today in Science. Rodents that consumed the drug also saw improvements in their insulin sensitivity and blood glucose quantities. In rats with NASH, the drug reduced fibrosis, the scarring that can cause cirrhosis and liver failure. The team also showed that it reversed diabetes in rats. Comparing the doses that provide these benefits with the doses that trigger side effects, the researchers determined that the slow-release version is safer than the liver-targeted drug.The study suggests that this gentler version of DNP could be useful for treating diabetes and NAFLD, Shulman says. It reduces fat buildup and corrects defective liver metabolism of glucose, so “it’s getting at the root cause of these diseases.” He and his colleagues plan further animal studies of the drug and hope to move on to safety trials in people.Hepatologist Sean Koppe of the University of Illinois Hospital & Health Sciences System in Chicago says that the results justify testing the drug in humans. “They show it has a broad window between therapeutic and toxic levels,” he says. Loomba says that the drug’s ability to curb fibrosis, one of the hallmarks of NASH, is encouraging, and he also supports safety trials in people. “This preclinical data is extremely exciting,” he says.Koppe and Loomba agree that if DNP does prove to be safe and effective in further trials, it could win approval from FDA, despite its history. Banned drugs have made comebacks before. The prime example is thalidomide, which was outlawed in the 1960s because it caused birth defects but has now found a niche in the treatment of cancer and leprosy.last_img read more